Christopher Dennis Bastian Rowley

There is an intrinsic relationship between the structure and function of the human brain, which has motivated researchers to characterize the brain’s microstructure to gain a better understanding of how the brain functions. This talk will delve into the fascinating realm of using quantitative Magnetic Resonance Imaging (MRI) techniques to explore the intricate landscape of brain microstructure. By employing quantitative MRI methodologies, researchers can obtain insights into the spatial organization and composition of neural tissues at a microscopic level. This presentation will not only highlight the significance of quantitative MRI in studying various aspects of brain microstructure, such as myelin content, and iron-loading, but also focus on the crucial aspect of removing scanner-related biases. Addressing and mitigating these biases is essential for improving our ability to accurately detect changes in microstructure, ensuring robust and reliable outcomes. Through a comprehensive examination of qMRI metrics, analytical approaches, and bias correction methods, the talk aims to showcase the potential of qMRI as a powerful tool for unraveling the complexities of the brain's microstructural architecture.