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Juan Fortea Ormaechea

Wed, Jun 05

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Bowerman Room, Dobell

Biphasic model of cortical macro and microstructural changes in AD

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Juan Fortea Ormaechea
Juan Fortea Ormaechea

Time & Location

Jun 05, 2019, 11:30 AM – 12:30 PM

Bowerman Room, Dobell, Douglas Mental Health University Institute, Blvd LaSalle, Verdun

About the Event

There is conflicting evidence on the effects of amyloid and tau on brain structure in preclinical AD. We will review the studies in familial and sporadic preclinical AD leading to the proposal of a novel biphasic model for the cortical macro and microstructural changes in preclinical AD. This model reconciles conflicting evidence and has direct implications in current clinical trials and hypothetical natural history models of the disease.

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